Temporal alignment of tissue and arterial data and selection of integration start times for the H/sub 2//sup 15/O autoradiographic CBF model in PET
RF Muzic, AD Nelson, F Miraldi - IEEE transactions on medical …, 1993 - ieeexplore.ieee.org
RF Muzic, AD Nelson, F Miraldi
IEEE transactions on medical imaging, 1993•ieeexplore.ieee.orgA technique has been developed and tested that provides an automated method of
temporally aligning the PET tissue activity curve with the arterial activity curve for
quantification of cerebral blood flow using the H/sub 2//sup 15/O autoradiographic model.
This technique not only determines the relative time delay between the two curves, but also
provides the start time of integration. Variability in computing global cerebral blood flow
using this technique is shown to be less than that obtained by trained observers manually …
temporally aligning the PET tissue activity curve with the arterial activity curve for
quantification of cerebral blood flow using the H/sub 2//sup 15/O autoradiographic model.
This technique not only determines the relative time delay between the two curves, but also
provides the start time of integration. Variability in computing global cerebral blood flow
using this technique is shown to be less than that obtained by trained observers manually …
A technique has been developed and tested that provides an automated method of temporally aligning the PET tissue activity curve with the arterial activity curve for quantification of cerebral blood flow using the H/sub 2//sup 15/O autoradiographic model. This technique not only determines the relative time delay between the two curves, but also provides the start time of integration. Variability in computing global cerebral blood flow using this technique is shown to be less than that obtained by trained observers manually selecting parameters and at least as good as that obtained by using another automated alignment technique.< >
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